After brushing your teeth, dry the top row of your teeth with a tissue.
Push the button on the bottom of the pen to prime before the first use. It can take multiple pushes (up to 20) to get that first drop to appear on the brush tip. Then, wipe the brush on a tissue to remove excess serum before you begin. Apply a single, thin layer of serum to each tooth across the top row (1-2 pushes is enough for up to 4 teeth) and wait 10 to 15 seconds for the serum to dry and form a clear coating. Dry the bottom row of your teeth and repeat the process. Make sure to avoid eating and drinking for 30 minutes. Once the serum dries on your teeth, it can last safely for hours. Remove the dried serum by brushing your teeth. For best results, we recommend leaving the serum on overnight until your next brushing.